About

I am currently working as a principal data scientist in the lab led by Dr. Yinyin Yuan at The University of Texas MD Anderson Cancer Center (2023 to present). Prior to that, I was a postdoc in Dr. Yuan’s lab at the Institute of Cancer Research (ICR), UK (2020 to 2023), and received my Ph.D. in Optics, Photonics and Image Processing at Ecole Centrale Marseille, France (2016 to 2019).

Within the broader field of computational pathology for cancer research, my work focuses on developing interpretable, clinically meaningful, and biologically grounded AI workflows that quantify tissue microenvironments, characterize pollutant-associated remodeling, and integrate pathology with spatial omics to reveal microenvironmental mechanisms of disease

I’ll be joining the University of Utah and Huntsman Cancer Institute as a tenure-track Assistant Professor this coming fall.

News

Selected Publications

• VitaminP: cross-modal learning enables whole-cell segmentation from routine histology
  Yasin Shokrollahi, Karina B Pinao Gonzales, Elizve N Barrientos Toro, Paul Acosta, Patient Mosaic Team, Pingjun Chen, Yinyin Yuan, Xiaoxi Pan. Under review.
• AI-guided spatial path-omics reveals pollutant-induced microenvironment reprogramming in lung adenocarcinoma
  Xiaoxi Pan, Alexandria Lau, Maria Esther Salvatierra, Simon P. Castillo, Jake Leighton, Frank R. Rojas, B. Leticia Rodriguez, Paul H Acosta, Lakshmi Kakarala, Wei Lu, Ou Shi, Claudio A. Arrechedera, Heladio P. Ibarguen, Shanyu Zhang, Idania Lubo, Maria Gabriela Raso, Lulu Shang, Carmen Behrens, Ignacio I. Wistuba, Cara Haymaker, Luisa Maren Solis Soto, Yinyin Yuan. Under review.
• AI-derived tumor-infiltrating lymphocytes enhance the prediction of pathologic complete response in an early-stage triple-negative breast cancer prospective trial
  Xiaoxi Pan, Caner Ercan, Zhongya Wang, Roland L. Bassett, Karina B Pinao Gonzales, Gaiane M. Rauch, Beatriz E. Adrada, Rosalind P. Candelaria, Debu Tripathy, Jennifer K. Litton, Sharon H. Giordano, Vicente Valero, Banu Arun, Alyson Clayborn, Kiran Virani, Jason White, Qingqing Ding, Aysegul A. Sahin, William Fraser Symmans, Clinton Yam, Lei Huo, Yinyin Yuan. In revision.
• The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma
  Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Ho Kwan Alvin Cheung, Juvenal Baena, Takahiro Karasaki, Claire Wilson, Marco Sereno, Selvaraju Veeriah, Sarah Aitken, Allan Hackshaw, Andrew Nicholson, Mariam Jamal-Hanjani, Charles Swanton, Yinyin Yuan, John Le Quesne, David Moore. Nature Cancer, 2024.
• Gompertz growth with a shared carrying capacity optimally simulates primary and metastatic tumor growth dynamics
  Pirmin Schlicke, Preethi Korangath,Xiaoxi Pan, Caner Ercan, Kathleen Gabrielson, Lyndsey Werhane, Yinyin Yuan, Sebastien Benzekry, Robert Ivkov, and Heiko Enderling. British Journal of Cancer, 2026.
• Tumor microenvironment transcriptional activity enables robust stratification of chemotherapy response in triple-negative breast cancer
  Yaoyi Dai, Xiaoxi Pan, Shuai Guo, Shuangxi Ji, Shaolong Cao, Matthew Montierth, Yujie Jiang, Leming Shi, Shabnam Shalapour, Gloria V Echeverria, Lucy Yates, Johan Staaf, Jeffrey T Chang, Bora Lim, Yinyin Yuan, Wenyi Wang. Cell Reports Medicine, 2026.
• Multi-view separable pyramid network for AD prediction at MCI Stage by 18F-FDG brain PET imaging
  Xiaoxi Pan, Trong-Le Phan, Mouloud Adel,Caroline Fossati, Thierry Gaidon, Julien Wojak, Eric Guedj. IEEE Transactions on Medical Imaging, 2021.

Service & Talks

• Invited talk at BCB Seminar Series, Houston, US, Apr 2026.
• Invited talk at 4th Oncological Data Science Symposium, Slat Lake City, US, Apr 2026.
• Hot Topics Panelist at USCAP, San Antonio, US, Mar 2026.
• Invited talk at IDSO fellowship seminar, Houston, US, Oct 2025.
• Invited talk at MDA Colorectal Cancer Integromics seminar, Houston, US, May 2025.
• Invited talk at TMC AI summit workshop, Houston, US, Feb 2025.
• Invited talk at divisional Grand Rounds, Houston, US, Feb 2025.
• Meta-reviewer of ISBI 2025.
• Organization committee of a monthly seminar in the department of Translational Molecular Pathology, 2024-2025.
• Guest lecture for the course of Probabilities in Bioinformatics at Rice University, Houston, US, Apr 2024 and 2025.
• Invited talk at GSBS Cancer Biology Program retreat, Houston, US, Nov 2023.
• Invited talk at Omics to AI workshop, Alan Turing Institute, London, UK, May 2022.
• Co-organizer of a tutorial at ICIP, Online, Sep 2021.